Seasonal Allergies – Root Causes and Fixes
Not Just a Benign Nuisance
Seasonal allergies, also known as hay fever or allergic rhinitis, were first recognized in 1870.1 Its prevalence has steadily risen since the 1950s.2 According to CDC, more than one in four adults suffer from seasonal allergies.3
Seasonal allergies (causing runny or stuffy nose, sneezing, itchy eyes, nose, or throat, coughing, insomnia, and fatigue) are more than just a nuisance and should be taken seriously – they are canaries in the coal mine, telling the status of our immune system, which may be confused, losing tolerance, overreacting to benign things like pollen and even food. When the immune system, akin to the city’s police department, is in disarray, all kinds of disorders can manifest. In addition, studies call seasonal allergy an invisible killer because it along with medication side effects has been documented in many cases to cause accidents.4
The Root Causes
What is the underlining cause(s) of seasonal allergy? Do not scapegoat pollen. Studies have consistently found allergy prevalence is lower in rural areas with heavy pollen than in urban areas with less pollen. Furthermore, in developing countries such as China and India, season allergies were hardly heard of 40 years ago when there was more pollen. With rapid industrialization and urbanization, which comes with less pollen, developing countries are now catching up with and even surpassing the developed countries.
My personal experience may shed more light on this issue. I came to the United States in 1993. At the time, I had not heard of seasonal allergies in China. Within a couple weeks after the school started, a few Chinese students who came earlier told me “Seasonal allergy is a new and annoying problem, but you won’t get it if you don’t get it within the first five years.” Well, I got it in the fourth year. At the worst time, it vexed me three times each year – winter, spring, and fall. The worst part was the eyes – felt like they were being pricked by hundreds of needles, and the medications didn’t help much. Why were so many Chinese students, who were free of seasonal allergies while in China, developing allergies after living 3-5 years in the US? The prevailing theory maintains that there are more trees, grass, and thus more pollen here than in China.
In fact, that is not true. Before 1993 when I came to the states there were more trees and grass and thus more pollen in China than there are now. But there were almost no seasonal allergies then – at least I had never heard of it. With rapid urbanization and thus fewer trees and other plants, now seasonal allergies have reached epidemic proportions in China.
It cannot be clearer that pollen is not the root cause of seasonal allergies, rather it’s a messenger.
Another smokescreen worth debunking is the so-called hygiene theory claiming seasonal allergies and other diseases arise from the overly clean environment lacking germs, as our immune system was not well trained. Well, do households with lower income have higher rates of seasonal allergies and other disorders because they are cleaner? And why did so many students coming to the US during the 1980s and 1990s from developing countries like China develop seasonal allergies in 4 or 5 years? Do not forget they grew up in an environment with little sanitation. The hygiene theory makes little sense.
So, what is driving the rise in seasonal allergies? Clearly, it is not genes, and it is not aging. The only possible culprits are the environmental risk factors. A major problem is the toxic chemicals in the food we eat, the water we drink, the air we breathe, and the personal care products and household items we use. This is not a red herring – studies have clearly shown toxic chemicals in the environment weaken our immune system and induce allergic disorders.5-10
Apart from all the toxic chemicals sneaking into our bodies, anything detrimental to our immune system can contribute to seasonal allergies. For instance, studies have shown gut dysbiosis (overgrowth of pathogenic bacteria) and leaky gut can dysregulate the immune system and induce or exacerbate seasonal allergies.11-14 In particular, it is well established scientifically and empirically that gluten sensitivity can induce leaky gut which in turn confuses the immune system leading to seasonal allergies.15-18
Stress is another contributor. Stress damages our immune system and induces dysbiosis as well as leaky gut which in turn exacerbates seasonal allergy.19-24
Of course, we are what we eat – micronutrient deficiency weakens the immune system. In particular, vitamin D deficiency has been shown to contribute to immune-related disorders and seasonal allergies.25-27
The Fixes
Getting rid of seasonal allergies is much easier than healing most other chronic diseases. I fixed my severe three-times-a-year allergy eight years ago, and you can do it too. But keep in mind, no disorders will go away unless the underlying causes are addressed. Avoiding pollen (the messenger rather than the root cause) is not a fix and hardly feasible. And medications such as antihistamines, decongestants, and nasal corticosteroids masking the symptoms may have insidious long-term side effects. To address the root causes, take the following actions:
Clean out the Indoor Toxic Chemicals
- Dump all non-essential synthetic materials including clothing and containers, which constantly emit VOC (volatile organic compounds). Take this seriously – over 5,000 tons of 33 potentially harmful VOCs were emitted in California alone in 2020.28
- Replace chemical-based cleaning products with non-toxic alternatives – many options are available on the market, and you can make your own products by using white vinegar, baking soda, and hydrogen peroxide. Studies have shown conventional cleaning products are very toxic.29,30
- Minimize the use of personal care products containing toxic chemicals such as formaldehyde, lead and mercury.31,32 Again, there are non-toxic options available on the market and you just need to look for them.
- Avoid using air fresheners and scented candles, as they can release harmful chemicals into the air.33-35
- Keep an eye out for mold and dust mites, which can provoke your immune system and exacerbate your seasonal allergies.36,37
- To keep indoor air clean and fresh, regularly open windows to allow fresh air to circulate, use a high-quality air filter, reduce humidity during wet seasons, and clean every room regularly.
Eat Organic Food
Regardless of all the misinformation pumped out by the special interest groups and the uninformed, it is a simple fact that organic food (meat, grains, vegetables, and fruits) contains much less synthetic pesticides/fertilizers and more nutrients. If you cannot afford it, consider growing your own. And keep in mind that no matter how well you eat, only about 10% of the vitamin D we need is from food. You need more sun exposure or take supplements to get your vitamin D to the optimal level.
And it is imperative to drink clean water – nowadays, our tap water is more like a chemical soup than anything else. Do not forget, we are not only what we eat but also what we drink.
Watch Out for Food Sensitivity
Food sensitivity, also known as food intolerance, is more insidious than food allergy. Unlike the latter, food sensitivity often triggers immune responses without apparent symptoms. Common food sensitivities include gluten, dairy, soy, and egg white. While food allergy affects 1-2% of adults and less than 10% of children, food sensitivity is estimated to affect up to 20% of the population.38 Food sensitivity can be detected by testing IgG antibodies in the blood.
The test of IgG antibodies is scientific and reliable and relatively inexpensive. For instance, Life Extension tests 96 foods for $196. However, not everyone with high levels of these antibodies has symptoms. The most reliable method to figure out if food sensitivity is an issue for you is through an elimination diet – excluding gluten, dairy, eggs, and other foods (e.g., nuts) that you suspect might be problematic from your diet for 4-8 weeks. If there is no improvement in symptoms, food sensitivity is likely not your problem. If your symptoms improve, you can identify the offending food by reintroducing the eliminated foods one at a time.
If you decide to try an elimination diet, do it rigorously. Food contamination can confuse even the most meticulous minds. According to an FDA report, some individuals’ immune systems adversely react to an intake of 0.4 milligrams of gluten per day (about 0.008% of a teaspoon, or 1/9 of a sesame seed).39
Manage Your Stress
Stress is a real health killer – it affects every system in our body. Those who can manage it will survive and thrive, while those who don’t will be in jeopardy. We all experience stress from time to time, and managing it is easier said than done. However, learning how to better manage it can make a big difference. There is a wealth of information available online and in great books – we just need to take the time to learn.
Finally, bear in mind that addressing seasonal allergies is more than just saving the canary in the coal mine – it can prevent deadly explosions. Tackling these root causes will be the best investment you’ve ever made, as it reduces the risk of all other maladies. After all, health is our most valuable asset.
References
- Platts-Mills TA. The allergy epidemics: 1870-2010. J Allergy Clin Immunol. 2015 Jul;136(1):3-13. doi: 10.1016/j.jaci.2015.03.048. PMID: 26145982; PMCID: PMC4617537.
- The Nature of Allergy. Science and Technology – Sixth Report. UK Parliament. https://publications.parliament.uk/pa/ld200607/ldselect/ldsctech/166/16605.htm
- Diagnosed Allergic Conditions in Adults: United States, 2021. https://www.cdc.gov/nchs/products/databriefs/db460.htm?form=MG0AV3
- Akesaka M, Shigeoka H. “Invisible Killer”: Seasonal Allergies And Accidents. August 2023. https://www.nber.org/system/files/working_papers/w31593/w31593.pdf
- Takano H, Inoue KI. Environmental pollution and allergies. J Toxicol Pathol. 2017 Jul;30(3):193-199. doi: 10.1293/tox.2017-0028. Epub 2017 May 26. PMID: 28798526; PMCID: PMC5545671.
- Yang SN, Hsieh CC, Kuo HF, et al. The effects of environmental toxins on allergic inflammation. Allergy Asthma Immunol Res. 2014 Nov;6(6):478-84. doi: 10.4168/aair.2014.6.6.478. Epub 2014 Oct 15. PMID: 25374746; PMCID: PMC4214967.
- Peden D, Reed CE. Environmental and occupational allergies. J Allergy Clin Immunol. 2010 Feb;125(2 Suppl 2):S150-60. doi: 10.1016/j.jaci.2009.10.073. PMID: 20176257.
- Verscheure P, Honnay O, Speybroeck N, et al. Impact of environmental nitrogen pollution on pollen allergy: A scoping review. Sci Total Environ. 2023 Oct 1;893:164801. doi: 10.1016/j.scitotenv.2023.164801. Epub 2023 Jun 14. PMID: 37321510.
- D’Amato G, D’Amato M. Climate change, air pollution, pollen allergy and extreme atmospheric events. Curr Opin Pediatr. 2023 Jun 1;35(3):356-361. doi: 10.1097/MOP.0000000000001237. Epub 2023 Mar 14. PMID: 36917187.
- Levetin E, Van de Water P. Environmental contributions to allergic disease. Curr Allergy Asthma Rep. 2001 Nov;1(6):506-14. doi: 10.1007/s11882-001-0059-6. PMID: 11892080.
- Pantazi AC, Mihai CM, Balasa AL, et al. Relationship between Gut Microbiota and Allergies in Children: A Literature Review. Nutrients. 2023 May 29;15(11):2529. doi: 10.3390/nu15112529. PMID: 37299492; PMCID: PMC10255222.
- Augustine T, Kumar M, Al Khodor S, van Panhuys N. Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes. Clin Rev Allergy Immunol. 2023 Aug;65(1):43-71. doi: 10.1007/s12016-022-08939-9. Epub 2022 Jun 1. PMID: 35648372; PMCID: PMC10326151.
- Myles IA. Allergy as a Disease of Dysbiosis: Is It Time to Shift the Treatment Paradigm? Front Cell Infect Microbiol. 2019 Mar 7;9:50. doi: 10.3389/fcimb.2019.00050. PMID: 30899699; PMCID: PMC6416200.
- Niewiem M, Grzybowska-Chlebowczyk U. Intestinal Barrier Permeability in Allergic Diseases. Nutrients. 2022 Apr 30;14(9):1893. doi: 10.3390/nu14091893. PMID: 35565858; PMCID: PMC9101724.
- Losurdo G, Principi M, Iannone A, et al. Extra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm. World J Gastroenterol. 2018 Apr 14;24(14):1521-1530. doi: 10.3748/wjg.v24.i14.1521. PMID: 29662290; PMCID: PMC5897856.
- Puccetti A, Saverino D, Opri R, et al. Immune Response to Rotavirus and Gluten Sensitivity. J Immunol Res. 2018 Mar 15;2018:9419204. doi: 10.1155/2018/9419204. PMID: 29736406; PMCID: PMC5875030.
- Gluten Intolerance and Spring Allergies https://drlesawerner.com/health-blog/f/gluten-intolerance-and-spring-allergies
- How Gluten Can Contribute to Seasonal Allergies. https://rootcausemedicalclinics.com/gluten-and-seasonal-allergies/
- Bains JS, Sharkey KA. Stress and immunity – the circuit makes the difference. Nat Immunol. 2022 Aug;23(8):1137-1139. doi: 10.1038/s41590-022-01276-1. PMID: 35864244.
- Cleveland Clinic. Yes, There Is Such a Thing as Stress Sickness. December 1, 2023. https://health.clevelandclinic.org/what-happens-when-your-immune-system-gets-stressed-out
- Geng S, Yang L, Cheng F, et al. Gut Microbiota Are Associated With Psychological Stress-Induced Defections in Intestinal and Blood-Brain Barriers. Front Microbiol. 2020 Jan 15;10:3067. doi: 10.3389/fmicb.2019.03067. PMID: 32010111; PMCID: PMC6974438.
- La Torre D, Van Oudenhove L, Vanuytsel T, Verbeke K. Psychosocial stress-induced intestinal permeability in healthy humans: What is the evidence? Neurobiol Stress. 2023 Oct 6;27:100579. doi: 10.1016/j.ynstr.2023.100579. PMID: 37842017; PMCID: PMC10569989.
- Is stress making your allergy symptoms worse? https://www.health.harvard.edu/diseases-and-conditions/is-stress-making-your-allergy-symptoms-worse#:~:text=%22We%20don’t%20know%20why,worse%20allergy%20symptoms%20than%20usual.
- Patterson AM, Yildiz VO, Klatt MD, Malarkey WB. Perceived stress predicts allergy flares. Ann Allergy Asthma Immunol. 2014 Apr;112(4):317-21. doi: 10.1016/j.anai.2013.07.013. Epub 2013 Aug 6. PMID: 24428966; PMCID: PMC4120667.
- Zhang P. The Role of Diet and Nutrition in Allergic Diseases. Nutrients. 2023 Aug 22;15(17):3683. doi: 10.3390/nu15173683. PMID: 37686715; PMCID: PMC10490368.
- Bener A, Ehlayel MS, Bener HZ, Hamid Q. The impact of Vitamin D deficiency on asthma, allergic rhinitis and wheezing in children: An emerging public health problem. J Family Community Med. 2014 Sep;21(3):154-61. doi: 10.4103/2230-8229.142967. PMID: 25374465; PMCID: PMC4214003.
- Mirzakhani H, Al-Garawi A, Weiss ST, Litonjua AA. Vitamin D and the development of allergic disease: how important is it? Clin Exp Allergy. 2015 Jan;45(1):114-25. doi: 10.1111/cea.12430. PMID: 25307157; PMCID: PMC4369152.
- Knox KE, Dodson RE, Rudel RA, et al. Identifying Toxic Consumer Products: A Novel Data Set Reveals Air Emissions of Potent Carcinogens, Reproductive Toxicants, and Developmental Toxicants. Environ Sci Technol. 2023 May 16;57(19):7454-7465. doi: 10.1021/acs.est.2c07247. Epub 2023 May 2. PMID: 37129244; PMCID: PMC10193581.
- https://www.ewg.org/news-insights/news-release/2023/09/cleaning-products-emit-hundreds-hazardous-chemicals-new-study
- Temkin AM, Geller SL, Swanson SA, et al. Volatile organic compounds emitted by conventional and “green” cleaning products in the U.S. market. Chemosphere. 2023 Nov;341:139570. doi: 10.1016/j.chemosphere.2023.139570. Epub 2023 Sep 12. PMID: 37709066.
- Johnson PI, Favela K, Jarin J, et al. Chemicals of concern in personal care products used by women of color in three communities of California. J Expo Sci Environ Epidemiol. 2022 Nov;32(6):864-876. doi: 10.1038/s41370-022-00485-y. Epub 2022 Nov 2. PMID: 36323919; PMCID: PMC9628299.
- Sheikh K. Many Personal Care Products Contain Harmful Chemicals. Here’s What to Do About It. NYT. Updated Feb. 24, 2023. https://www.nytimes.com/2023/02/15/well/live/personal-care-products-chemicals.html.
- Nazir Z, Habib A, Ali T, Ghouri H, Haque MA. The unknown risks of scented candles! what science has to say: an editorial. Ann Med Surg (Lond). 2023 Nov 17;86(1):16-17. doi: 10.1097/MS9.0000000000001524. PMID: 38222738; PMCID: PMC10783381.
- The Guardian. Too many smelly candles? Here’s how scents impact the air quality in your home. 2023. https://www.theguardian.com/lifeandstyle/2023/jan/09/too-many-smelly-candles-heres-how-scents-impact-the-air-quality-in-your-home
- Columbia University. Do Air Fresheners Impact Our Health? February 5, 2024. https://www.columbiadoctors.org/news/do-air-fresheners-impact-our-health#:~:text=And%20there%20is%20growing%20evidence,to%20numerous%20adverse%20health%20outcomes.
- Kraft S, Buchenauer L, Polte T. Mold, Mycotoxins and a Dysregulated Immune System: A Combination of Concern? Int J Mol Sci. 2021 Nov 12;22(22):12269. doi: 10.3390/ijms222212269. PMID: 34830149; PMCID: PMC8619365.
- Jacquet A. Innate immune responses in house dust mite allergy. ISRN Allergy. 2013 Feb 28;2013:735031. doi: 10.1155/2013/735031. PMID: 23724247; PMCID: PMC3658386.
- Tuck CJ, Biesiekierski JR, Schmid-Grendelmeier P, Pohl D. Food Intolerances. Nutrients. 2019 Jul 22;11(7):1684. doi: 10.3390/nu11071684. PMID: 31336652; PMCID: PMC6682924
- Office of Food Safety Center of Food Safety and Applied Nutrition Food and Drug Administration. Health Hazard Assessment for Gluten Exposure in Individuals with Celiac Disease: Determination of Tolerable Daily Intake Levels and Levels of Concern for Gluten.